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Numb contributes to renal fibrosis by promoting tubular epithelial cell cycle arrest at G2/M
Numb is a multifunctional protein involved in diverse cellular processes. However, the function of Numb in kidney remains unclear. Here, we reported that Numb is expressed in renal tubules and glomeruli in normal adult kidney. Numb expression was upregulated in fibrotic kidneys induced by unilateral...
Autores principales: | Zhu, Fengxin, Liu, Wei, Li, Tang, Wan, Jiao, Tian, Jianwei, Zhou, Zhanmei, Li, Hao, Liu, Youhua, Hou, Fan Fan, Nie, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041930/ https://www.ncbi.nlm.nih.gov/pubmed/27016419 http://dx.doi.org/10.18632/oncotarget.8238 |
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