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Sciellin mediates mesenchymal-to-epithelial transition in colorectal cancer hepatic metastasis

Hepatic metastasis is the major cause of mortality in colorectal cancer (CRC) patients. Using proteomic analysis, we found sciellin (SCEL) to be specifically expressed in hepatic metastatic CRC cell lines. SCEL knockdown increased CRC cell migration and invasion, while overexpression had the opposit...

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Detalles Bibliográficos
Autores principales: Chou, Chuan-Kai, Fan, Chi-Chen, Lin, Pei-Shan, Liao, Pei-Yu, Tung, Jia-Chen, Hsieh, Chang-Hsun, Hung, Mien-Chie, Chen, Chung-Hsuan, Chang, Wei-Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041940/
https://www.ncbi.nlm.nih.gov/pubmed/27013588
http://dx.doi.org/10.18632/oncotarget.8264