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TRPV4 channels regulate tumor angiogenesis via modulation of Rho/Rho kinase pathway

Targeting angiogenesis is considered a promising therapy for cancer. Besides curtailing soluble factor mediated tumor angiogenesis, understanding the unexplored regulation of angiogenesis by mechanical cues may lead to the identification of novel therapeutic targets. We have recently shown that expr...

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Detalles Bibliográficos
Autores principales: Thoppil, Roslin J., Cappelli, Holly C., Adapala, Ravi K., Kanugula, Anantha K., Paruchuri, Sailaja, Thodeti, Charles K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041949/
https://www.ncbi.nlm.nih.gov/pubmed/27029071
http://dx.doi.org/10.18632/oncotarget.8405