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miR-509-3p is clinically significant and strongly attenuates cellular migration and multi-cellular spheroids in ovarian cancer

Ovarian cancer presents as an aggressive, advanced stage cancer with widespread metastases that depend primarily on multicellular spheroids in the peritoneal fluid. To identify new druggable pathways related to metastatic progression and spheroid formation, we integrated microRNA and mRNA sequencing...

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Detalles Bibliográficos
Autores principales: Pan, Yinghong, Robertson, Gordon, Pedersen, Lykke, Lim, Emilia, Hernandez-Herrera, Anadulce, Rowat, Amy C., Patil, Sagar L., Chan, Clara K., Wen, Yunfei, Zhang, Xinna, Basu-Roy, Upal, Mansukhani, Alka, Chu, Andy, Sipahimalani, Payal, Bowlby, Reanne, Brooks, Denise, Thiessen, Nina, Coarfa, Cristian, Ma, Yussanne, Moore, Richard A., Schein, Jacquie E., Mungall, Andrew J., Liu, Jinsong, Pecot, Chad V., Sood, Anil K., Jones, Steven J.M., Marra, Marco A., Gunaratne, Preethi H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041955/
https://www.ncbi.nlm.nih.gov/pubmed/27036018
http://dx.doi.org/10.18632/oncotarget.8412