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Transcriptional regulation of the potential tumor suppressor ABI3 gene in thyroid carcinomas: interplay between methylation and NKX2-1 availability

We previously reported that ABI3 expression was decreased in thyroid cancer tissues and that ectopic expression of ABI3 in a follicular thyroid carcinoma cell line delayed cell cycle progression and inhibited cell proliferation, invasion, migration and tumor formation in athymic mice. These data ind...

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Detalles Bibliográficos
Autores principales: Moraes, Lais, Galrão, Ana Luiza R., Rubió, Ileana, Cerutti, Janete M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041957/
https://www.ncbi.nlm.nih.gov/pubmed/27036019
http://dx.doi.org/10.18632/oncotarget.8416