A high-content EMT screen identifies multiple receptor tyrosine kinase inhibitors with activity on TGFβ receptor

An epithelial to mesenchymal transition (EMT) enables epithelial tumor cells to break out of the primary tumor mass and to metastasize. Understanding the molecular mechanisms driving EMT in more detail will provide important tools to interfere with the metastatic process. To identify pharmacological...

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Detalles Bibliográficos
Autores principales: Lotz-Jenne, Carina, Lüthi, Urs, Ackerknecht, Sabine, Lehembre, François, Fink, Tobias, Stritt, Manuel, Wirth, Matthias, Pavan, Simona, Bill, Ruben, Regenass, Urs, Christofori, Gerhard, Meyer-Schaller, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041959/
https://www.ncbi.nlm.nih.gov/pubmed/27036020
http://dx.doi.org/10.18632/oncotarget.8418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041959/
https://www.ncbi.nlm.nih.gov/pubmed/27036020
http://dx.doi.org/10.18632/oncotarget.8418

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