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A high-content EMT screen identifies multiple receptor tyrosine kinase inhibitors with activity on TGFβ receptor
An epithelial to mesenchymal transition (EMT) enables epithelial tumor cells to break out of the primary tumor mass and to metastasize. Understanding the molecular mechanisms driving EMT in more detail will provide important tools to interfere with the metastatic process. To identify pharmacological...
Autores principales: | Lotz-Jenne, Carina, Lüthi, Urs, Ackerknecht, Sabine, Lehembre, François, Fink, Tobias, Stritt, Manuel, Wirth, Matthias, Pavan, Simona, Bill, Ruben, Regenass, Urs, Christofori, Gerhard, Meyer-Schaller, Nathalie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041959/ https://www.ncbi.nlm.nih.gov/pubmed/27036020 http://dx.doi.org/10.18632/oncotarget.8418 |
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