Cargando…

REST reduction is essential for hypoxia-induced neuroendocrine differentiation of prostate cancer cells by activating autophagy signaling

Prostate cancer (PCa) with neuroendocrine differentiation (NED) is tightly associated with hormone refractory PCa (HRPC), an aggressive form of cancer that is nearly impossible to treat. Determining the mechanism of the development of NED may yield novel therapeutic strategies for HRPC. Here, we fir...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Tzu-Ping, Chang, Yi-Ting, Lee, Sung-Yuan, Campbell, Mel, Wang, Tien-Chiao, Shen, Shu-Huei, Chung, Hsiao-Jen, Chang, Yen-Hwa, Chiu, Allen W., Pan, Chin-Chen, Lin, Chi-Hung, Chu, Cheng-Ying, Kung, Hsing-Jien, Cheng, Chia-Yang, Chang, Pei-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041970/
https://www.ncbi.nlm.nih.gov/pubmed/27034167
http://dx.doi.org/10.18632/oncotarget.8433