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Sumoylation of TCF21 downregulates the transcriptional activity of estrogen receptor-alpha

Aberrant estrogen receptor-α (ERα) signaling is recognized as a major contributor to the development of breast cancer. However, the molecular mechanism underlying the regulation of ERα in breast cancer is still inconclusive. In this study, we showed that the transcription factor 21 (TCF21) interacte...

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Detalles Bibliográficos
Autores principales: Ao, Xiang, Li, Shujing, Xu, Zhaowei, Yang, Yangyang, Chen, Min, Jiang, Xiao, Wu, Huijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041976/
https://www.ncbi.nlm.nih.gov/pubmed/27028856
http://dx.doi.org/10.18632/oncotarget.8354