Inhibition of melanocortin 1 receptor slows melanoma growth, reduces tumor heterogeneity and increases survival

Melanoma risk is increased in patients with mutations of melanocortin 1 receptor (MC1R) yet the basis for the increased risk remains unknown. Here we report in vivo evidence supporting a critical role for MC1R in regulating melanoma tumor growth and determining overall survival time. Inhibition of M...

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Detalles Bibliográficos
Autores principales: Kansal, Rita G., McCravy, Matthew S., Basham, Jacob H., Earl, Joshua A., McMurray, Stacy L., Starner, Chelsey J., Whitt, Michael A., Albritton, Lorraine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041983/
https://www.ncbi.nlm.nih.gov/pubmed/27028866
http://dx.doi.org/10.18632/oncotarget.8372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041983/
https://www.ncbi.nlm.nih.gov/pubmed/27028866
http://dx.doi.org/10.18632/oncotarget.8372

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