IFN-α potentiates the direct and immune-mediated antitumor effects of epigenetic drugs on both metastatic and stem cells of colorectal cancer

Epigenetic alterations, including dysregulated DNA methylation and histone modifications, govern the progression of colorectal cancer (CRC). Cancer cells exploit epigenetic regulation to control cellular pathways, including apoptotic and metastatic signals. Since aberrations in epigenome can be phar...

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Detalles Bibliográficos
Autores principales: Buoncervello, Maria, Romagnoli, Giulia, Buccarelli, Mariachiara, Fragale, Alessandra, Toschi, Elena, Parlato, Stefania, Lucchetti, Donatella, Macchia, Daniele, Spada, Massimo, Canini, Irene, Sanchez, Massimo, Falchi, Mario, Musella, Martina, Biffoni, Mauro, Belardelli, Filippo, Capone, Imerio, Sgambato, Alessandro, Vitiani, Lucia Ricci, Gabriele, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041985/
https://www.ncbi.nlm.nih.gov/pubmed/27028869
http://dx.doi.org/10.18632/oncotarget.8379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041985/
https://www.ncbi.nlm.nih.gov/pubmed/27028869
http://dx.doi.org/10.18632/oncotarget.8379

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