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Genetic variants of CHRNA5-A3 and CHRNB3-A6 predict survival of patients with advanced non-small cell lung cancer

Nicotinic acetylcholine receptors (nAChRs) play a key role in carcinogenesis and progression of lung cancer; and polymorphisms in CHRNA5-A3 and CHRNB3-A6, two gene clusters encoding nAChR subunits, have been associated with lung cancer risk. In this study, we investigated whether variants in the two...

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Detalles Bibliográficos
Autores principales: Wang, Yang, Peng, Xiaonu, Zhu, Lijun, Hu, Likuan, Song, Yipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041990/
https://www.ncbi.nlm.nih.gov/pubmed/27050379
http://dx.doi.org/10.18632/oncotarget.8510