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Genetic and epigenetic factors affect RET gene expression in breast cancer cell lines and influence survival in patients

Germline and somatic mutations play a crucial role in breast cancer (BC), driving the initiation, progression, response to therapy and outcome of the disease. Hormonal therapy is limited to patients with tumors expressing steroid hormone receptors, such as estrogen receptor (ER), nevertheless resist...

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Detalles Bibliográficos
Autores principales: Griseri, Paola, Garrone, Ornella, Lo Sardo, Alessandra, Monteverde, Martino, Rusmini, Marta, Tonissi, Federica, Merlano, Marco, Bruzzi, Paolo, Lo Nigro, Cristiana, Ceccherini, Isabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041993/
https://www.ncbi.nlm.nih.gov/pubmed/27034161
http://dx.doi.org/10.18632/oncotarget.8417