Cancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs

Emerging evidence indicates that ionizing radiation (IR) and chemotherapy activate Type I interferon (IFN) signaling in tumor and host cells. However, the mechanism of induction is poorly understood. We identified a novel radioprotective role for the DEXH box RNA helicase LGP2 (DHX58) through its su...

Descripción completa

Detalles Bibliográficos
Autores principales: Ranoa, Diana Rose E., Parekh, Akash D., Pitroda, Sean P., Huang, Xiaona, Darga, Thomas, Wong, Anthony C., Huang, Lei, Andrade, Jorge, Staley, Jonathan P., Satoh, Takashi, Akira, Shizuo, Weichselbaum, Ralph R., Khodarev, Nikolai N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041995/
https://www.ncbi.nlm.nih.gov/pubmed/27034163
http://dx.doi.org/10.18632/oncotarget.8420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041995/
https://www.ncbi.nlm.nih.gov/pubmed/27034163
http://dx.doi.org/10.18632/oncotarget.8420

Ejemplares similares