High fat diet increases melanoma cell growth in the bone marrow by inducing osteopontin and interleukin 6

The impact of metabolic stress induced by obesity on the bone marrow melanoma niche is largely unknown. Here we employed diet induced obese mice model, where mice received high-fat (HFD) or normal diet (ND) for 6 weeks before challenge with B16F10 melanoma cells. Tumor size, bone loss and osteoclast...

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Detalles Bibliográficos
Autores principales: Chen, Guang-Liang, Luo, Yubin, Eriksson, Daniel, Meng, Xianyi, Qian, Cheng, Bäuerle, Tobias, Chen, Xiao-Xiang, Schett, Georg, Bozec, Aline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042005/
https://www.ncbi.nlm.nih.gov/pubmed/27049717
http://dx.doi.org/10.18632/oncotarget.8474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042005/
https://www.ncbi.nlm.nih.gov/pubmed/27049717
http://dx.doi.org/10.18632/oncotarget.8474

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