Tumor suppressor PRSS8 targets Sphk1/S1P/Stat3/Akt signaling in colorectal cancer

PRSS8 is a membrane-anchored serine protease prostasin and has been shown an association with carcinogenesis. Herein we found that PRSS8 expression was significantly reduced in colorectal adenomas and adenocarcinomas. The decreased PRSS8 was well correlated with clinical stages, poor differentiation...

Descripción completa

Detalles Bibliográficos
Autores principales: Bao, Yonghua, Li, Kai, Guo, Yongchen, Wang, Qian, Li, Zexin, Yang, Yiqiong, Chen, Zhiguo, Wang, Jianguo, Zhao, Weixing, Zhang, Huijuan, Chen, Jiwang, Dong, Huali, Shen, Kui, Diamond, Alan M., Yang, Wancai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042014/
https://www.ncbi.nlm.nih.gov/pubmed/27050145
http://dx.doi.org/10.18632/oncotarget.8511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042014/
https://www.ncbi.nlm.nih.gov/pubmed/27050145
http://dx.doi.org/10.18632/oncotarget.8511

Ejemplares similares