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Tumor suppressor PRSS8 targets Sphk1/S1P/Stat3/Akt signaling in colorectal cancer
PRSS8 is a membrane-anchored serine protease prostasin and has been shown an association with carcinogenesis. Herein we found that PRSS8 expression was significantly reduced in colorectal adenomas and adenocarcinomas. The decreased PRSS8 was well correlated with clinical stages, poor differentiation...
Autores principales: | Bao, Yonghua, Li, Kai, Guo, Yongchen, Wang, Qian, Li, Zexin, Yang, Yiqiong, Chen, Zhiguo, Wang, Jianguo, Zhao, Weixing, Zhang, Huijuan, Chen, Jiwang, Dong, Huali, Shen, Kui, Diamond, Alan M., Yang, Wancai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042014/ https://www.ncbi.nlm.nih.gov/pubmed/27050145 http://dx.doi.org/10.18632/oncotarget.8511 |
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