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The physical interaction of p53 and plakoglobin is necessary for their synergistic inhibition of migration and invasion

Plakoglobin (PG) is a paralog of β-catenin with similar adhesive, but contrasting signalling functions. Although β-catenin has well-known oncogenic function, PG generally acts as a tumor/metastasis suppressor by mechanisms that are just beginning to be deciphered. Previously, we showed that PG inter...

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Detalles Bibliográficos
Autores principales: Alaee, Mahsa, Padda, Amarjot, Mehrabani, Vahedah, Churchill, Lucas, Pasdar, Manijeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042024/
https://www.ncbi.nlm.nih.gov/pubmed/27058623
http://dx.doi.org/10.18632/oncotarget.8616