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The physical interaction of p53 and plakoglobin is necessary for their synergistic inhibition of migration and invasion
Plakoglobin (PG) is a paralog of β-catenin with similar adhesive, but contrasting signalling functions. Although β-catenin has well-known oncogenic function, PG generally acts as a tumor/metastasis suppressor by mechanisms that are just beginning to be deciphered. Previously, we showed that PG inter...
Autores principales: | Alaee, Mahsa, Padda, Amarjot, Mehrabani, Vahedah, Churchill, Lucas, Pasdar, Manijeh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042024/ https://www.ncbi.nlm.nih.gov/pubmed/27058623 http://dx.doi.org/10.18632/oncotarget.8616 |
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