Pharmacokinetics and pharmacodynamics of mepolizumab, an anti–interleukin 5 monoclonal antibody, in healthy Japanese male subjects

Interleukin 5 (IL‐5) and eosinophils are thought to play an important role in the pathology of asthma. This study evaluated the pharmacokinetics, pharmacodynamics, safety, and tolerability of mepolizumab, a humanized anti‐IL5 IgG1 monoclonal antibody, in development for the treatment of severe eosin...

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Detalles Bibliográficos
Autores principales: Tsukamoto, Naohiro, Takahashi, Naoki, Itoh, Hiroshi, Pouliquen, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042051/
https://www.ncbi.nlm.nih.gov/pubmed/27138023
http://dx.doi.org/10.1002/cpdd.205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042051/
https://www.ncbi.nlm.nih.gov/pubmed/27138023
http://dx.doi.org/10.1002/cpdd.205

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