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Selected CSF biomarkers indicate no evidence of early neuroinflammation in Huntington disease

OBJECTIVE: To investigate CSF biomarkers of neuroinflammation and neurodegeneration in Huntington disease (HD) gene-expansion carriers compared to controls and to investigate these biomarkers in association with clinical HD rating scales and disease burden score. METHODS: We collected CSF from 32 pr...

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Detalles Bibliográficos
Autores principales: Vinther-Jensen, Tua, Börnsen, Lars, Budtz-Jørgensen, Esben, Ammitzbøll, Cecilie, Larsen, Ida U., Hjermind, Lena E., Sellebjerg, Finn, Nielsen, Jørgen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042104/
https://www.ncbi.nlm.nih.gov/pubmed/27734023
http://dx.doi.org/10.1212/NXI.0000000000000287