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Specificity of broad protein interaction surfaces for proteins with multiple binding partners

Analysis of protein-protein interaction networks has revealed the presence of proteins with multiple interaction ligand proteins, such as hub proteins. For such proteins, multiple ligands would be predicted as interacting partners when predicting all-to-all protein-protein interactions (PPIs). In th...

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Detalles Bibliográficos
Autores principales: Uchikoga, Nobuyuki, Matsuzaki, Yuri, Ohue, Masahito, Akiyama, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society of Japan (BSJ) 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042157/
https://www.ncbi.nlm.nih.gov/pubmed/27924264
http://dx.doi.org/10.2142/biophysico.13.0_105