Molecular mechanisms of substrate specificities of uridinecytidine kinase

A uridine-cytidine kinase (UCK) catalyzes the phosphorylation of uridine (Urd) and cytidine (Cyd) and plays a significant role in the pyrimidine-nucleotide salvage pathway. Unlike ordinary ones, UCK from Thermus thermophilus HB8 (ttCK) loses catalytic activity on Urd due to lack of a substrate bindi...

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Detalles Bibliográficos
Autores principales: Tanaka, Wataru, Shoji, Mitsuo, Tomoike, Fumiaki, Ujiie, Yuzuru, Hanaoka, Kyohei, Harada, Ryuhei, Kayanuma, Megumi, Kamiya, Katsumasa, Ishida, Toyokazu, Masui, Ryoji, Kuramitsu, Seiki, Shigeta, Yasuteru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society of Japan (BSJ) 2016
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042166/
https://www.ncbi.nlm.nih.gov/pubmed/27924260
http://dx.doi.org/10.2142/biophysico.13.0_77

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042166/
https://www.ncbi.nlm.nih.gov/pubmed/27924260
http://dx.doi.org/10.2142/biophysico.13.0_77

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