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Molecular mechanisms of substrate specificities of uridinecytidine kinase

A uridine-cytidine kinase (UCK) catalyzes the phosphorylation of uridine (Urd) and cytidine (Cyd) and plays a significant role in the pyrimidine-nucleotide salvage pathway. Unlike ordinary ones, UCK from Thermus thermophilus HB8 (ttCK) loses catalytic activity on Urd due to lack of a substrate bindi...

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Detalles Bibliográficos
Autores principales:	Tanaka, Wataru, Shoji, Mitsuo, Tomoike, Fumiaki, Ujiie, Yuzuru, Hanaoka, Kyohei, Harada, Ryuhei, Kayanuma, Megumi, Kamiya, Katsumasa, Ishida, Toyokazu, Masui, Ryoji, Kuramitsu, Seiki, Shigeta, Yasuteru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Biophysical Society of Japan (BSJ) 2016
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042166/ https://www.ncbi.nlm.nih.gov/pubmed/27924260 http://dx.doi.org/10.2142/biophysico.13.0_77

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