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Structural characterization of single nucleotide variants at ligand binding sites and enzyme active sites of human proteins

Functional sites on proteins play an important role in various molecular interactions and reactions between proteins and other molecules. Thus, mutations in functional sites can severely affect the overall phenotype. Progress of genome sequencing projects has yielded a wealth of information on singl...

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Detalles Bibliográficos
Autores principales: Yamada, Kazunori D., Nishi, Hafumi, Nakata, Junichi, Kinoshita, Kengo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society of Japan (BSJ) 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042176/
https://www.ncbi.nlm.nih.gov/pubmed/27924270
http://dx.doi.org/10.2142/biophysico.13.0_157