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Structural characterization of single nucleotide variants at ligand binding sites and enzyme active sites of human proteins
Functional sites on proteins play an important role in various molecular interactions and reactions between proteins and other molecules. Thus, mutations in functional sites can severely affect the overall phenotype. Progress of genome sequencing projects has yielded a wealth of information on singl...
Autores principales: | Yamada, Kazunori D., Nishi, Hafumi, Nakata, Junichi, Kinoshita, Kengo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society of Japan (BSJ)
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042176/ https://www.ncbi.nlm.nih.gov/pubmed/27924270 http://dx.doi.org/10.2142/biophysico.13.0_157 |
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