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Ruxolitinib in the treatment of polycythemia vera: patient selection and special considerations

The discovery of JAK2 V617F mutation in the mid-2000s started to fill the gap between clinical presentation of polycythemia vera (PV), first described by Vaquez at the end of the 19th century, and spontaneous erythroid colony formation, reported by Prchal and Axelrad in the mid-1970s. The knowledge...

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Detalles Bibliográficos
Autores principales: Blum, Sabine, Martins, Filipe, Alberio, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042185/
https://www.ncbi.nlm.nih.gov/pubmed/27729820
http://dx.doi.org/10.2147/JBM.S102471