TopBP1 contributes to the chemoresistance in non-small cell lung cancer through upregulation of p53

Resistance to chemotherapeutic drugs is a major obstacle in non-small cell lung cancer (NSCLC) therapy. The molecular determinants of NSCLC resistance to doxorubicin are unknown. In the present study, we investigated whether topoisomerase IIβ binding protein 1 (TopBP1) was involved in the chemoresis...

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Detalles Bibliográficos
Autores principales: Lv, Yinxiang, Huo, Yanan, Yu, Xican, Liu, Rongrong, Zhang, Shufen, Zheng, Xiaoxiao, Zhang, Xianning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042189/
https://www.ncbi.nlm.nih.gov/pubmed/27729767
http://dx.doi.org/10.2147/DDDT.S90705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042189/
https://www.ncbi.nlm.nih.gov/pubmed/27729767
http://dx.doi.org/10.2147/DDDT.S90705

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