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Evaluation of optimum conditions for pachyman encapsulated in poly(d,l-lactic acid) nanospheres by response surface methodology and results of a related in vitro study

This study aimed to optimize the preparation conditions of pachyman (PHY)-loaded poly(d,l-lactic acid) (PLA) (PHYP) nanospheres by response surface methodology, explore their characteristics, and assess their effects on splenic lymphocytes. Double emulsion solvent evaporation was used to synthesize...

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Detalles Bibliográficos
Autores principales: Zheng, Sisi, Luo, Li, Bo, Ruonan, Liu, Zhenguang, Xing, Jie, Niu, Yale, Hu, Yuanliang, Liu, Jiaguo, Wang, Deyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042191/
https://www.ncbi.nlm.nih.gov/pubmed/27729787
http://dx.doi.org/10.2147/IJN.S115742