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Evaluation of optimum conditions for pachyman encapsulated in poly(d,l-lactic acid) nanospheres by response surface methodology and results of a related in vitro study
This study aimed to optimize the preparation conditions of pachyman (PHY)-loaded poly(d,l-lactic acid) (PLA) (PHYP) nanospheres by response surface methodology, explore their characteristics, and assess their effects on splenic lymphocytes. Double emulsion solvent evaporation was used to synthesize...
Autores principales: | Zheng, Sisi, Luo, Li, Bo, Ruonan, Liu, Zhenguang, Xing, Jie, Niu, Yale, Hu, Yuanliang, Liu, Jiaguo, Wang, Deyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042191/ https://www.ncbi.nlm.nih.gov/pubmed/27729787 http://dx.doi.org/10.2147/IJN.S115742 |
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