Sustained release of hepatocyte growth factor by cationic self-assembling peptide/heparin hybrid hydrogel improves β-cell survival and function through modulating inflammatory response

Inflammatory response is a major cause of grafts dysfunction in islet transplantation. Hepatocyte growth factor (HGF) had shown anti-inflammatory activity in multiple diseases. In this study, we aim to deliver HGF by self-assembling peptide/heparin (SAP/Hep) hybrid gel to protect β-cell from inflamm...

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Detalles Bibliográficos
Autores principales: Liu, Shuyun, Zhang, Lanlan, Cheng, Jingqiu, Lu, Yanrong, Liu, Jingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042198/
https://www.ncbi.nlm.nih.gov/pubmed/27729786
http://dx.doi.org/10.2147/IJN.S108921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042198/
https://www.ncbi.nlm.nih.gov/pubmed/27729786
http://dx.doi.org/10.2147/IJN.S108921

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