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Parkinson-associated risk variant in enhancer element produces subtle effect on target gene expression
Genome-wide association studies (GWAS) have identified numerous genetic variants associated with complex diseases but mechanistic insights are impeded by the lack of understanding of how specific risk variants functionally contribute to the underlying pathogenesis(1). It has been proposed that cis-a...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042324/ https://www.ncbi.nlm.nih.gov/pubmed/27096366 http://dx.doi.org/10.1038/nature17939 |