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Full-Length Isoform Sequencing Reveals Novel Transcripts and Substantial Transcriptional Overlaps in a Herpesvirus

Whole transcriptome studies have become essential for understanding the complexity of genetic regulation. However, the conventionally applied short-read sequencing platforms cannot be used to reliably distinguish between many transcript isoforms. The Pacific Biosciences (PacBio) RS II platform is ca...

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Detalles Bibliográficos
Autores principales: Tombácz, Dóra, Csabai, Zsolt, Oláh, Péter, Balázs, Zsolt, Likó, István, Zsigmond, Laura, Sharon, Donald, Snyder, Michael, Boldogkői, Zsolt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042381/
https://www.ncbi.nlm.nih.gov/pubmed/27685795
http://dx.doi.org/10.1371/journal.pone.0162868