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Full-Length Isoform Sequencing Reveals Novel Transcripts and Substantial Transcriptional Overlaps in a Herpesvirus
Whole transcriptome studies have become essential for understanding the complexity of genetic regulation. However, the conventionally applied short-read sequencing platforms cannot be used to reliably distinguish between many transcript isoforms. The Pacific Biosciences (PacBio) RS II platform is ca...
Autores principales: | Tombácz, Dóra, Csabai, Zsolt, Oláh, Péter, Balázs, Zsolt, Likó, István, Zsigmond, Laura, Sharon, Donald, Snyder, Michael, Boldogkői, Zsolt |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042381/ https://www.ncbi.nlm.nih.gov/pubmed/27685795 http://dx.doi.org/10.1371/journal.pone.0162868 |
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