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Targeting the Hippo Signaling Pathway for Tissue Regeneration and Cancer Therapy
The Hippo signaling pathway is a highly-conserved developmental pathway that plays an essential role in organ size control, tumor suppression, tissue regeneration and stem cell self-renewal. The YES-associated protein (YAP) and the transcriptional co-activator with PDZ-binding motif (TAZ) are two im...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042386/ https://www.ncbi.nlm.nih.gov/pubmed/27589805 http://dx.doi.org/10.3390/genes7090055 |