Cargando…

Regulation of BLM Nucleolar Localization

Defects in coordinated ribosomal RNA (rRNA) transcription in the nucleolus cause cellular and organismal growth deficiencies. Bloom’s syndrome, an autosomal recessive human disorder caused by mutated recQ-like helicase BLM, presents with growth defects suggestive of underlying defects in rRNA transc...

Descripción completa

Detalles Bibliográficos
Autores principales: Tangeman, Larissa, McIlhatton, Michael A., Grierson, Patrick, Groden, Joanna, Acharya, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042399/
https://www.ncbi.nlm.nih.gov/pubmed/27657136
http://dx.doi.org/10.3390/genes7090069