Ups and Downs: Mechanisms of Repeat Instability in the Fragile X-Related Disorders

The Fragile X-related disorders (FXDs) are a group of clinical conditions resulting from the expansion of a CGG/CCG-repeat tract in exon 1 of the Fragile X mental retardation 1 (FMR1) gene. While expansions of the repeat tract predominate, contractions are also seen with the net result being that in...

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Detalles Bibliográficos
Autores principales: Zhao, Xiao-Nan, Usdin, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042400/
https://www.ncbi.nlm.nih.gov/pubmed/27657135
http://dx.doi.org/10.3390/genes7090070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042400/
https://www.ncbi.nlm.nih.gov/pubmed/27657135
http://dx.doi.org/10.3390/genes7090070

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