Structural Details of Ufd1 Binding to p97 and Their Functional Implications in ER-Associated Degradation

The hexameric ATPase p97 has been implicated in diverse cellular processes through interactions with many different adaptor proteins at its N-terminal domain. Among these, the Ufd1-Npl4 heterodimer is a major adaptor, and the p97-Ufd1-Npl4 complex plays an essential role in endoplasmic reticulum-ass...

Descripción completa

Detalles Bibliográficos
Autores principales: Le, Le Thi My, Kang, Wonchull, Kim, Ji-Yun, Le, Oanh Thi Tu, Lee, Sang Yoon, Yang, Jin Kuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042407/
https://www.ncbi.nlm.nih.gov/pubmed/27684549
http://dx.doi.org/10.1371/journal.pone.0163394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042407/
https://www.ncbi.nlm.nih.gov/pubmed/27684549
http://dx.doi.org/10.1371/journal.pone.0163394

Ejemplares similares