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Structural Details of Ufd1 Binding to p97 and Their Functional Implications in ER-Associated Degradation

The hexameric ATPase p97 has been implicated in diverse cellular processes through interactions with many different adaptor proteins at its N-terminal domain. Among these, the Ufd1-Npl4 heterodimer is a major adaptor, and the p97-Ufd1-Npl4 complex plays an essential role in endoplasmic reticulum-ass...

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Detalles Bibliográficos
Autores principales:	Le, Le Thi My, Kang, Wonchull, Kim, Ji-Yun, Le, Oanh Thi Tu, Lee, Sang Yoon, Yang, Jin Kuk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042407/ https://www.ncbi.nlm.nih.gov/pubmed/27684549 http://dx.doi.org/10.1371/journal.pone.0163394

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