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Changes in the Plasticity of HIV-1 Nef RNA during the Evolution of the North American Epidemic

Because of a high mutation rate, HIV exists as a viral swarm of many sequence variants evolving under various selective pressures from the human immune system. Although the Nef gene codes for the most immunogenic of HIV accessory proteins, which alone makes it of great interest to HIV research, it a...

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Detalles Bibliográficos
Autores principales: Manzourolajdad, Amirhossein, Gonzalez, Mileidy, Spouge, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042412/
https://www.ncbi.nlm.nih.gov/pubmed/27685447
http://dx.doi.org/10.1371/journal.pone.0163688