Optimizing Trial Designs for Targeted Therapies

An important objective in the development of targeted therapies is to identify the populations where the treatment under consideration has positive benefit risk balance. We consider pivotal clinical trials, where the efficacy of a treatment is tested in an overall population and/or in a pre-specifie...

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Detalles Bibliográficos
Autores principales: Ondra, Thomas, Jobjörnsson, Sebastian, Beckman, Robert A., Burman, Carl-Fredrik, König, Franz, Stallard, Nigel, Posch, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042421/
https://www.ncbi.nlm.nih.gov/pubmed/27684573
http://dx.doi.org/10.1371/journal.pone.0163726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042421/
https://www.ncbi.nlm.nih.gov/pubmed/27684573
http://dx.doi.org/10.1371/journal.pone.0163726

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