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The CARD9 Polymorphisms rs4077515, rs10870077 and rs10781499 Are Uncoupled from Susceptibility to and Severity of Pulmonary Tuberculosis

Genetic variants in the CARD9 gene predispose to inflammatory disorders and chronic infectious diseases. Tuberculosis (TB), a chronic infectious disease affecting the lung, is lethal in Card9-deficient mice. We hypothesized that polymorphisms in the CARD9 gene influence TB progression and disease-as...

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Detalles Bibliográficos
Autores principales: Streata, Ioana, Weiner, January, Iannaconne, Marco, McEwen, Gayle, Ciontea, Marius Sorin, Olaru, Marian, Capparelli, Rosanna, Ioana, Mihai, Kaufmann, Stefan H. E., Dorhoi, Anca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042433/
https://www.ncbi.nlm.nih.gov/pubmed/27684065
http://dx.doi.org/10.1371/journal.pone.0163662