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Identification of β Clamp-DNA Interaction Regions That Impair the Ability of E. coli to Tolerate Specific Classes of DNA Damage

The E. coli dnaN-encoded β sliding clamp protein plays a pivotal role in managing the actions on DNA of the 5 bacterial DNA polymerases, proteins involved in mismatch repair, as well as several additional proteins involved in DNA replication. Results of in vitro experiments indicate that the loading...

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Detalles Bibliográficos
Autores principales: Nanfara, Michael T., Babu, Vignesh M. P., Ghazy, Mohamed A., Sutton, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042465/
https://www.ncbi.nlm.nih.gov/pubmed/27685804
http://dx.doi.org/10.1371/journal.pone.0163643