Neurotoxic Antibodies against the Prion Protein Do Not Trigger Prion Replication

Prions are the infectious agents causing transmissible spongiform encephalopathies (TSE), progressive, inexorably lethal neurological diseases. Antibodies targeting the globular domain (GD) of the cellular prion protein PrP(C) trigger a neurotoxic syndrome morphologically and molecularly similar to...

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Detalles Bibliográficos
Autores principales: Frontzek, Karl, Pfammatter, Manuela, Sorce, Silvia, Senatore, Assunta, Schwarz, Petra, Moos, Rita, Frauenknecht, Katrin, Hornemann, Simone, Aguzzi, Adriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042507/
https://www.ncbi.nlm.nih.gov/pubmed/27684562
http://dx.doi.org/10.1371/journal.pone.0163601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042507/
https://www.ncbi.nlm.nih.gov/pubmed/27684562
http://dx.doi.org/10.1371/journal.pone.0163601

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