K-Ras Activation Induces Differential Sensitivity to Sulfur Amino Acid Limitation and Deprivation and to Oxidative and Anti-Oxidative Stress in Mouse Fibroblasts

BACKGROUND: Cancer cells have an increased demand for amino acids and require transport even of non-essential amino acids to support their increased proliferation rate. Besides their major role as protein synthesis precursors, the two proteinogenic sulfur-containing amino acids, methionine and cyste...

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Detalles Bibliográficos
Autores principales: De Sanctis, Gaia, Spinelli, Michela, Vanoni, Marco, Sacco, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042513/
https://www.ncbi.nlm.nih.gov/pubmed/27685888
http://dx.doi.org/10.1371/journal.pone.0163790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042513/
https://www.ncbi.nlm.nih.gov/pubmed/27685888
http://dx.doi.org/10.1371/journal.pone.0163790

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