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Tumor Infiltrating Lymphocytes Affect the Outcome of Patients with Operable Triple-Negative Breast Cancer in Combination with Mutated Amino Acid Classes

BACKGROUND: Stromal tumor infiltrating lymphocytes (TILs) density is an outcome predictor in triple-negative breast cancer (TNBC). Herein we asked whether TILs are related to coding mutation load and to the chemical class of the resulting mutated amino acids, i.e., charged, polar, and hydrophobic mu...

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Detalles Bibliográficos
Autores principales: Kotoula, Vassiliki, Lakis, Sotiris, Vlachos, Ioannis S., Giannoulatou, Eleni, Zagouri, Flora, Alexopoulou, Zoi, Gogas, Helen, Pectasides, Dimitrios, Aravantinos, Gerasimos, Efstratiou, Ioannis, Pentheroudakis, George, Papadopoulou, Kyriaki, Chatzopoulos, Kyriakos, Papakostas, Pavlos, Sotiropoulou, Maria, Nicolaou, Irene, Razis, Evangelia, Psyrri, Amanda, Kosmidis, Paris, Papadimitriou, Christos, Fountzilas, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042538/
https://www.ncbi.nlm.nih.gov/pubmed/27685159
http://dx.doi.org/10.1371/journal.pone.0163138