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Calcific Aortic Valve Disease Is Associated with Layer-Specific Alterations in Collagen Architecture
Disorganization of the valve extracellular matrix (ECM) is a hallmark of calcific aortic valve disease (CAVD). However, while microarchitectural features of the ECM can strongly influence the biological and mechanical behavior of tissues, little is known about the ECM microarchitecture in CAVD. In t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042542/ https://www.ncbi.nlm.nih.gov/pubmed/27685946 http://dx.doi.org/10.1371/journal.pone.0163858 |