Calcific Aortic Valve Disease Is Associated with Layer-Specific Alterations in Collagen Architecture

Disorganization of the valve extracellular matrix (ECM) is a hallmark of calcific aortic valve disease (CAVD). However, while microarchitectural features of the ECM can strongly influence the biological and mechanical behavior of tissues, little is known about the ECM microarchitecture in CAVD. In t...

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Detalles Bibliográficos
Autores principales: Hutson, Heather N., Marohl, Taylor, Anderson, Matthew, Eliceiri, Kevin, Campagnola, Paul, Masters, Kristyn S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042542/
https://www.ncbi.nlm.nih.gov/pubmed/27685946
http://dx.doi.org/10.1371/journal.pone.0163858

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