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Effect of Polyaryl Hydrocarbons on Cytotoxicity in Monocytic Cells: Potential Role of Cytochromes P450 and Oxidative Stress Pathways

BACKGROUND: Benzo(a)pyrene (BaP), naphthalene (NPh), phenanthrene (Phe), benzo(a)antharacene (BeA), and benzo(b)fluoranthene (BeF) are known carcinogenic polyaryl hydrocarbons (PAHs) present in cigarette smoke. This study was designed to examine the relative effect of these constituents on the cytot...

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Detalles Bibliográficos
Autores principales: Ranjit, Sabina, Midde, Narasimha M., Sinha, Namita, Patters, Benjamin J., Rahman, Mohammad A., Cory, Theodore J., Rao, P. S. S., Kumar, Santosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042547/
https://www.ncbi.nlm.nih.gov/pubmed/27684561
http://dx.doi.org/10.1371/journal.pone.0163827