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Role of BMP receptor traffic in synaptic growth defects in an ALS model

TAR DNA-binding protein 43 (TDP-43) is genetically and functionally linked to amyotrophic lateral sclerosis (ALS) and regulates transcription, splicing, and transport of thousands of RNA targets that function in diverse cellular pathways. In ALS, pathologically altered TDP-43 is believed to lead to...

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Detalles Bibliográficos
Autores principales: Deshpande, Mugdha, Feiger, Zachary, Shilton, Amanda K., Luo, Christina C., Silverman, Ethan, Rodal, Avital A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042577/
https://www.ncbi.nlm.nih.gov/pubmed/27535427
http://dx.doi.org/10.1091/mbc.E16-07-0519